Science
NAD+ in aging, metabolism, and neurodegeneration
Verdin E
2015 · DOI: 10.1126/science.aac4854 · PMID: 26785480
View Source ↗
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AeroPeptides supplies research-grade peptides for in-vitro and laboratory use only. Not for human or veterinary consumption.
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Cellular Health & Longevity
NAD+ (nicotinamide adenine dinucleotide) is an endogenous redox cofactor central to cellular bioenergetics and a substrate for the sirtuin, PARP, and CD38 enzyme families. A growing research literature has examined its role in metabolic, mitochondrial, and aging-biology pathways. For laboratory and research use only.
Third party tested
Certificate of Analysis — NAD+ (100mg)
Per-lot identity, purity, and endotoxin results are released as PDFs. Leave your email and we'll send the latest COA for this compound directly to your inbox.
Each lot is independently tested for identity, purity, and endotoxin. Full COA PDFs with HPLC traces and mass-spec spectra are available on request.
Research focus
Summary of contexts in which this compound appears in the preclinical literature. See cited studies for primary sources.
NAD+ (nicotinamide adenine dinucleotide) is an endogenous redox cofactor central to cellular bioenergetics and a substrate for the sirtuin, PARP, and CD38 enzyme families. A growing research literature has examined its role in metabolic, mitochondrial, and aging-biology pathways. For laboratory and research use only.
Technical specifications
Compound Information
Pyridine nucleotide coenzyme
Storage & Stability
Lyophilized (powder)
-20°C • long-term stable in sealed lyophilized form
Reconstituted
2-8°C • use within 14 days of reconstitution (shorter than peptide window)
Light
Photosensitive — protect from light; nicotinamide moiety degrades on UV exposure
Room temperature
Avoid extended exposure above 25°C; hygroscopic
Compound-specific notes
Distinct from peptide compounds — NAD+ is a small-molecule dinucleotide and undergoes hydrolysis in aqueous solution faster than most peptides. Reconstitute close to time of use.
Sources & references
Science
NAD+ in aging, metabolism, and neurodegeneration
Verdin E
2015 · DOI: 10.1126/science.aac4854 · PMID: 26785480
View Source ↗Cell Metabolism
Human trials exploring anti-aging medicines
Guarente L, Sinclair DA, Kroemer G
2024 · DOI: 10.1016/j.cmet.2023.12.007 · PMID: 38181790
View Source ↗Nature Metabolism
CD38 ecto-enzyme in immune cells is induced during aging and regulates NAD+ and NMN levels
Chini CCS, Peclat TR, Warner GM, et al.
2020 · DOI: 10.1038/s42255-020-00298-z · PMID: 33199925
View Source ↗Aging and Disease
Role and Potential Mechanisms of Nicotinamide Mononucleotide in Aging
Rahman SU, Qadeer A, Wu Z, et al.
2024 · DOI: 10.14336/AD.2023.0519-1 · PMID: 37548938
View Source ↗4 peer-reviewed references listed. Citations verified against NCBI PubMed records. For research and educational reference only — does not constitute medical advice.
Researcher FAQ
No. AeroPeptides materials are sold exclusively for in-vitro research and laboratory analytical use. They are not intended to diagnose, treat, cure, or prevent any disease, and are not approved for human or animal administration.
By placing an order, you confirm that you are a qualified researcher and that the material will be used in accordance with all applicable institutional and jurisdictional regulations.
Each lot is independently tested for identity, purity, and mass using HPLC and mass spectrometry. The COA lists the lot number, test date, assay results, and the laboratory that performed the analysis.
Public COA documents are being prepared. In the meantime, you can request a COA for your specific lot and we’ll email it within 1 business day.
Orders ship within 1 business day from the US. Lyophilized peptides are shipped with insulation appropriate to season; short-term ambient excursions during transit do not measurably affect potency.
On receipt, store at −20°C in the sealed vial until reconstitution. See the handling matrix for full storage parameters. Tracked shipping is included; we ship to all US states and most international destinations.
Most peptides are reconstituted with bacteriostatic water (BAC). The volume depends on the target working concentration. Use our Peptide Calculator to compute volume, U-100 insulin syringe units, and doses per vial from peptide mass and target dose.
Once reconstituted, store at 2–8°C and use within 30 days. Protect the vial from light during storage and handling.
Because peptides are temperature-sensitive research materials, we cannot accept returns of opened or unsealed vials. If a shipment arrives damaged or the seal is broken on arrival, contact us within 7 days and we’ll replace or refund.
See our full returns policy for details.
Don’t see your question? Contact our research team — we typically reply within one business day.
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⚠ Important research notice
Not for human consumption. This product is sold exclusively for research and educational purposes. It is not intended to diagnose, treat, cure, or prevent any disease.
All clinical trial data and research findings presented on this page are sourced from peer-reviewed journals and official publications. They are provided for educational reference only and should not be interpreted as medical advice or product claims.
By purchasing this product, you confirm that you are a qualified researcher and will use it in accordance with all applicable laws and regulations.