Human Reproduction Update
The kisspeptin-GnRH pathway in human reproductive health and disease
Skorupskaite K, George JT, Anderson RA
2014 · DOI: 10.1093/humupd/dmu009 · PMID: 24615662
View Source ↗
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Kisspeptin-10 is the C-terminal decapeptide of metastin, the active fragment of the KISS1 gene product. Published clinical and preclinical research has characterised its interaction with the KISS1R (GPR54) receptor in studies of hypothalamic GnRH neurosecretion and reproductive endocrinology. For laboratory and research use only.
Third party tested
Certificate of Analysis — KISSPEPTIN-10 (10mg)
Per-lot identity, purity, and endotoxin results are released as PDFs. Leave your email and we'll send the latest COA for this compound directly to your inbox.
Each lot is independently tested for identity, purity, and endotoxin. Full COA PDFs with HPLC traces and mass-spec spectra are available on request.
Research focus
Summary of contexts in which this compound appears in the preclinical literature. See cited studies for primary sources.
Kisspeptin-10 is the C-terminal decapeptide of metastin, the active fragment of the KISS1 gene product. Published clinical and preclinical research has characterised its interaction with the KISS1R (GPR54) receptor in studies of hypothalamic GnRH neurosecretion and reproductive endocrinology. For laboratory and research use only.
Technical specifications
Compound Information
Decapeptide (kisspeptin active fragment)
Storage & Stability
Lyophilized (powder)
-20°C • long-term stable in sealed lyophilized form
Reconstituted
2-8°C • use within 30 days of reconstitution
Light
Protect from light during storage and reconstitution
Room temperature
Short-term tolerant during shipping; minimise extended exposure above 25°C
Sources & references
Human Reproduction Update
The kisspeptin-GnRH pathway in human reproductive health and disease
Skorupskaite K, George JT, Anderson RA
2014 · DOI: 10.1093/humupd/dmu009 · PMID: 24615662
View Source ↗Reviews in Endocrine and Metabolic Disorders
The neuroendocrine physiology of kisspeptin in the human
Dhillo WS, Murphy KG, Bloom SR
2007 · DOI: 10.1007/s11154-007-9029-1 · PMID: 17323132
View Source ↗The Lancet Diabetes & Endocrinology
Pubertal development and regulation
Abreu AP, Kaiser UB
2016 · DOI: 10.1016/S2213-8587(15)00418-0 · PMID: 26852256
View Source ↗Molecular and Cellular Endocrinology
Hypothalamo-Pituitary axis and puberty
Spaziani M, Tarantino C, Tahani N, et al.
2021 · DOI: 10.1016/j.mce.2020.111094 · PMID: 33271219
View Source ↗Biochemistry (Moscow)
Role of Kisspeptin in Regulation of Reproductive and Immune Reactions
Gorbunova OL, Shirshev SV
2020 · DOI: 10.1134/S0006297920080015 · PMID: 33045946
View Source ↗5 peer-reviewed references listed. Citations verified against NCBI PubMed records. For research and educational reference only — does not constitute medical advice.
Researcher FAQ
No. AeroPeptides materials are sold exclusively for in-vitro research and laboratory analytical use. They are not intended to diagnose, treat, cure, or prevent any disease, and are not approved for human or animal administration.
By placing an order, you confirm that you are a qualified researcher and that the material will be used in accordance with all applicable institutional and jurisdictional regulations.
Each lot is independently tested for identity, purity, and mass using HPLC and mass spectrometry. The COA lists the lot number, test date, assay results, and the laboratory that performed the analysis.
Public COA documents are being prepared. In the meantime, you can request a COA for your specific lot and we’ll email it within 1 business day.
Orders ship within 1 business day from the US. Lyophilized peptides are shipped with insulation appropriate to season; short-term ambient excursions during transit do not measurably affect potency.
On receipt, store at −20°C in the sealed vial until reconstitution. See the handling matrix for full storage parameters. Tracked shipping is included; we ship to all US states and most international destinations.
Most peptides are reconstituted with bacteriostatic water (BAC). The volume depends on the target working concentration. Use our Peptide Calculator to compute volume, U-100 insulin syringe units, and doses per vial from peptide mass and target dose.
Once reconstituted, store at 2–8°C and use within 30 days. Protect the vial from light during storage and handling.
Because peptides are temperature-sensitive research materials, we cannot accept returns of opened or unsealed vials. If a shipment arrives damaged or the seal is broken on arrival, contact us within 7 days and we’ll replace or refund.
See our full returns policy for details.
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⚠ Important research notice
Not for human consumption. This product is sold exclusively for research and educational purposes. It is not intended to diagnose, treat, cure, or prevent any disease.
All clinical trial data and research findings presented on this page are sourced from peer-reviewed journals and official publications. They are provided for educational reference only and should not be interpreted as medical advice or product claims.
By purchasing this product, you confirm that you are a qualified researcher and will use it in accordance with all applicable laws and regulations.